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KPV (also known as Lys-Pro-Val or the α-MSH tripeptide fragment) is a naturally occurring short peptide derived from the C-terminal sequence of α-melanocyte-stimulating hormone (α-MSH). In preclinical research, KPV has demonstrated potent anti-inflammatory and immunomodulatory properties, helping to regulate cytokine activity and protect tissues from excessive inflammatory stress.
Because of its small size and stability, it has been studied as a simplified alternative to full-length α-MSH analogues, with interest in applications related to gut barrier function, skin inflammation, and systemic immune balance.
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Amino Acid Sequence: | Lys-Pro-Val |
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Molecular Weight: | 341.45 g/mol |
Molecular Formula: | C17H31N5O4 |
CAS Number: | 27255-71-8 |
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