Melanotan 2 10mg
$40.00
Melanotan 2, Melanotan-II, or MT-2 is a peptide that replicates the human alpha melanocyte-stimulating hormone α-MSH. The hormone is a melanocortin I receptor agonist for human pigmentation and stimulates production of emelanin, the pigment for hair and skin color. Melanotan 2 is popular among men and women for its multiple benefits.
Melanotan 2 promotes the tanning of the human skin, eyes, and hair without depending on the sun. It also supports many other functions, including triggering sexual arousal in men. MT-2 is also famous for its potential effects on appetite suppression and fat metabolism.
Do you have any problem?
- Gently swirl the Melanotan 2 solution to ensure the powder dissolves.
- Draw the desired dose into an insulin syringe.
- Start with a low dose to assess tolerance.
- Clean the injection site with a fatty layer.
- Injections under the skin are preferred due to the absorption speed into the bloodstream.
- Store the unreconstituted Melanotan 2 powder vial in a cool, dry place away from direct sunlight. Refrigeration of 2 to 8 degrees centigrade is recommended to maintain stability.
- Keep reconstituted solution refrigerated at all times and use the peptide within 30 days to ensure efficacy and potency.
- Active ingredient Melanotan 2 peptide (Ac-Nle-cyclo [Asp-His-D-Phe-Arg-Trp-Lys]-NH2)
- Lyophilized powder without additives
- Bacteriostatic water for reconstitution.
- Nausea
- Flushing
- Darkened moles and freckles
- Fatigue
- Shimizu, K. Inoue, and M. Mori, “The leptin-dependent and -independent melanocortin signaling system: regulation of feeding and energy expenditure,” J. Endocrinol., vol. 193, no. 1, pp. 1–9, Apr. 2007.
- Bjørbaek and A. N. Hollenberg, “Leptin and melanocortin signaling in the hypothalamus,” Vitam. Horm., vol. 65, pp. 281–311, 2002.
- Guo, K. Bakal, Y. Minokoshi, and A. N. Hollenberg, “Leptin Signaling Targets the Thyrotropin-Releasing Hormone Gene Promoter in Vivo,” Endocrinology, vol. 145, no. 5, pp. 2221–2227, May 2004.
- Toda et al., “Distinct effects of leptin and a melanocortin receptor agonist injected into medial hypothalamic nuclei on glucose uptake in peripheral tissues,” Diabetes, vol. 58, no. 12, pp. 2757–2765, Dec. 2009.
- A. York, S. Boghossian, and M. Park-York, “Melanocortin activity in the amygdala influences alcohol intake,” Pharmacol. Biochem. Behav., vol. 98, no. 1, pp. 112–119, Mar. 2011.
- Navarro, F. Carvajal, J. M. Lerma-Cabrera, I. Cubero, M. J. Picker, and T. E. Thiele, “Evidence that Melanocortin Receptor Agonist Melanotan-II Synergistically Augments the Ability of Naltrexone to Blunt Binge-Like Ethanol Intake in Male C57BL/6J Mice,” Alcohol. Clin. Exp. Res., vol. 39, no. 8, pp. 1425–1433, Aug. 2015.
- K. Y. Lau et al., “Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model,” Sci. Rep., vol. 11, no. 1, p. 4359, Feb. 2021, doi: 10.1038/s41598-021-83932-4.
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Purposes of Melanotan 2 in Research
Skin tanning
Melanotan 2 is primarily used for the promotion of melanin production in the skin. The results are a gradual, natural-looking tan. Melanotan 2 allows users to achieve a darker pigmentation without depending on the traditional tanning methods that require prolonged exposure to the sun.
Sunless tanning is especially beneficial for any one with a fair skin and prone to sunburn. The deep tan achieved using Melanotan 2 is known to last longer than conventional tans. This quality makes the peptide an excellent choice for those looking for extended results.
Enhancing libido
Melanotan 2 has a noticeable impact on sexual arousal and performance. It increases sexual desire and heightens sensitivity, improving the overall sexual experience. The peptide’s influence on the melanocortin system, which plays a significant role in sexual function regulation, is a major reason for this effect.
However, the extent of this benefit varies from one individual to the next. Melanotan is gaining popularity among people looking to naturally enhance their libido.
Appetite suppression
Melanotan 2 has appetite suppressing effects that make it an effective weight management tool. Users feel less hungry, which leads to reduction in calorie intake and supports weight loss efforts.
The appetite-suppressing effect of Melanotan 2 is especially helpful for those following a calorie-controlled diet. It helps reduce cravings and makes it easier to maintain a healthy eating plan. However, Melanotan 2 is an effective weight management tool and not a suitable substitute for a balanced diet and exercise.
Weight loss
Melanotan 2 fosters improved fat metabolism, which makes it appealing to those who want to loose their weight. The peptide promotes fat oxidation by helping the body break down stored fat more efficiently.
Melanotan 2 is an effective tool for any one struggling with stubborn fat deposits and wants to enhance the effects of their diet and exercise efforts. Some users report improved body composition with continued use of Melanotan 2.
Malanotan 2 Quantity and Forms
Quantity
Melanotan 2 is usually available in vials containing 10mg of the lyophilized powder.
Forms
Melanotan 2 is supplied as freeze-dried powder that requires reconstitution with included bacteriostatic water before use.
Instructions of Taking Melanotan
Storage
Malanotan’s Ingredients
How Does Melanotan 2 (MT-2) Work?
Melanotan 2 acts on the melanocortin receptors, especially MC1R, stimulating melanin production in melanocytes. The result is a gradual darkening of the skin.
Melanotan 2 also binds to MC4R and MC3R through mimicking α-MSH, which contribute to its effects on libido and appetite regulation.
Observed Benefits of Melanotan 2 (MT-2) in Research
Enhanced and long lasting skin tanning
Melanotan 2 enables users achieve a deeper tan with less UV exposure, reducing the risk of sunburn and skin damage. The tanning effect helps users achieve their desired skin tone with minimal effort for a long time. The tan fades gradually after stopping Melanotan 2, avoiding the sudden loss of pigmentation.
Improved libido
Melanotan 2 enhances sexual desire and performance in both men and women. It interacts with the melanocortin system, which plays a vital role in sexual function regulation. Melanotan helps users achieve spontaneous arousal and heightened sensitivity for fulfilling intimate experiences.
Appetite control
Melanotan 2 helps users experience a reduced sense of hunger, helping them adhere to their calorie-controlled diets more easily.
Fat loss
Melanotan 2 supports efficient fat burning that supports individuals in their efforts to achieve leaner physiques.
Who Should Use Melanotan 2 (MT-2) in Their Research?
People seeking a safer tan can achieve their desired results with Melanotan 2 without excessive sun exposure. This is beneficial for those in regions with limited sunlight or those who prefer to avoid tanning beds. People with fair skin can also achieve a gradual tan that uniformly covers the entire body.
Melanotan 2 is suitable for those looking to improve their sexual function and arousal levels.
The appetite-suppressing properties of Melanotan 2 make it suitable for individuals who want to improve the efficacy of their weight management plans.
Expected Effects of Melanotan 2 (MT-2)
The initial effects of Melanotan 2 include a slight shade in the skin color and improved sexual experiences. Other effects take effect with the continued use of the peptide.
When Will the Results of Melanotan 2 (MT-2) Become Obvious?
Initial pigmentation changes may occur within a few days with the optimal tanning effect occurring within 3 to 4 weeks of consistent use. The tanning speed depends on the skin type, dosage, and frequency of UV exposure.
Enhanced libido is apparent within hours of administering Melanotan 2. Users report immediate increase in sexual desire, heightened sensitivity, and arousal within a few hours. However, the results may vary depending on an individual’s personal physiology and underlying factors like overall health and hormonal balance.
Melanotn Dosage Guidelines
Initial phase
Users usually start with 0.25mg per day, increasing it gradually to 0.5 or 1mg daily within the first week. The approach allows the body to adjust to Melanotan while minimizing potential side effects.
Maintenance phase
After achieving the desired tanning level, the user should reduce to 0.5mg to 1mg per week. Lowering the dosage helps sustain the tan without excessive melanin production or unnecessary peptide use. Spacing out doses to every few days is sufficient for maintaining the tan.
Administration
Inject Melanotan 2 subcutaneously using an insulin syringe to ensure efficient absorption into the bloodstream. Always clean the injection site with an alcohol swab before administration to reduce infection risk. Rotate injection sites to prevent irritation and skin sensitivity over time.
UV exposure
Moderate sub exposure ensures optimal tanning results. Short sunbathing sessions or controlled use of tanning beds can help speed up the pigmentation process. However, users should cautious and avoid excessive UV exposer to prevent skin damage and sunburn.
Safety and Potential Side Effects
Melanotan 2 is considered safe when used responsibly. However, some users might experience side effects such as:
FAQs
Is Melanotan 2 (MT-2) legal?
Melanotan 2 is available for research purposes and not approved for medical use in many countries. The sale and use of Melanotan depends on the specific region, so potential users should check their local regulations before buying. Other countries allow use of Melanotan 2 for personal purposes.
How long does the tan last?
The tan lasts for months without continuous use depending on sun exposure and the individual skin type. The tan fades gradually over time instead of disappearing suddenly. Occasional maintenance doses and limited UV exposure are necessary to maintain the tanning the results. Proper hydration also helps improve the lifetime of the tan.
References
Gilhooley E, Daly S, McKenna D. Melanotan II User Experience: A Qualitative Study of Online Discussion Forums. Dermatology. 2021;237(6):995-999. doi: 10.1159/000514492. Epub 2021 Aug 31. PMID: 34464955.
Dorr RT, Lines R, Levine N, Brooks C, Xiang L, Hruby VJ, Hadley ME. Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study. Life Sci. 1996;58(20):1777-84. doi: 10.1016/0024-3205(96)00160-9. PMID: 8637402.
Ning McKenzie, Nathaly Gonzalez, Cathleen Huang, Devin Barzallo, Olivia Ware, Kieron Leslie, Poster presentationsPS09 User experiences of Melanotan II injection for tanning, British Journal of Dermatology, Volume 191, Issue Supplement_1, July 2024, Pages i179–i180, https://doi.org/10.1093/bjd/ljae090.380
“Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study. – PubMed – NCBI.” [Online]. Available: [Accessed: 15-May-2019]..
WESSELLS, H. , HRUBY, V. J., HACKETT, J. , HAN, G. , BALSE‐SRINIVASAN, P. and VANDERAH, T. W. (2003), MT‐II Induces Penile Erection via Brain and Spinal Mechanisms. Annals of the New York Academy of Sciences, 994: 90-95.
Wessells, H. (1998). Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: Doubleblind placebo controlled crossover study. Nature.com.
Amino Acid Sequence: | Ac-Nle-Cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-NH₂ |
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Molecular Weight: | 1024.18 g/mol |
Molecular Formula: | C50H69N15O9 |
CAS Number: | 121062-08-6 |