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What if you could benefit from the effects of your body’s natural growth hormone — without the cravings and without the crashes? Ipamorelin is a lab-created ghrelin derivative that does just that. Its natural counterpart stimulates appetite and fat storage while it releases growth hormone and helps you regulate your sleep-wake cycles. Ipamorelin was synthesized to do only one thing. It boosts your natural growth hormone pulses. No hunger spikes. No cortisol disruptions. No insulin swings.
Research shows Ipamorelin may shred stubborn fat, speed up muscle growth and post-workout recovery, have the potential to build bone density, and nudge people toward better, more restorative sleep by keeping the body’s natural rhythms on track. Alongside those effects, Ipamorelin might even improve skin and hair health.
Athletes, biohackers, and insomniacs research Ipamorelin to get the benefits of GH optimization — without the drawbacks. For anyone researching recovery, lean gains, GH decline, or better sleep.
Because quality matters. You need to know where your peptides come from. CellPeptides is an EU-based (we deliver to USA without any hassle and fast) research and scientific company that provides pure peptides for research purposes. Our lab facility in the EU is WHO/GMP and ISO 9001:2015 certified. Advancing peptide research is our sole mission.
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Ipamorelin is one of the most interesting synthetic peptides for health and recovery. How it works definitely deserves a closer look. Let’s go there, starting with the natural peptide hormone ghrelin — made in the cells lining the stomach. Ipamorelin was modeled after it, but with some important differences.
You’ve seen ghrelin called the hunger hormone. That a good name for it because, when your stomach is empty, ghrelin tells your brain to make you hungry. It also plays roles in regulating fat storage, the sleep-wake cycle, and gastrointestinal health.
Besides that, though, ghrelin triggers the release of growth hormone. It does that by binding to the growth hormone secretagogue receptor in the pituitary. That’s the job Ipamorelin targets — so it’s a more selective version of ghrelin. The parts athletes and others want, without the ones they don’t. Ipamorelin tells the pituitary gland to increase production of growth hormone; that’s what “secratagogue” means. That simple action? That has wide-ranging knock-on effects throughout the body.
Research has looked into its ability to boost lean muscle mass, zap body fat, lead to faster workout recovery, and more, precisely because it’s selective and doesn’t touch your insulin, cortisol, or prolactin levels.
Anyone curious about Ipamorelin soon runs into a serious problem — study of the growth hormone peptide has, unfortunately, been sorely neglected in the last few years. Since it stopped being considered as a treatment option for post-operative ileus (an intestinal problem some people encounter after surgery), research slowed down a little. For now, at least.
The current body of research still offers answers — and new studies are still coming out. You’ll find information about some of the most interesting practical applications here.
A boost in growth hormone production, research shows [1], consistently increases muscle protein synthesis — something that helps bodybuilders and athletes build lean muscle more quickly and that speeds up recovery after workout sessions.
Ipamorelin is still relatively understudied in this area, although some exciting research does exist [2, 3]. Anecdotal reports from athletes who have studied the effect ipamorelin has on their muscle growth, performance, and post-workout recovery are abundant, however, and with very promising results.
Growth hormone levels inevitably dwindle with age, and that decline is among the things that contribute to the most unwanted signs of aging. [4] Sagging, thinning, and more vulnerable skin. Wrinkles. Slower healing. Nobody looks forward to it, but it happens eventually.
Because Ipamorelin boosts fibroblast activity (or in plain English, it encourages the body to make more collagen), the existing research hints at interesting potential in “treating” wrinkles and sagging. [5] Some researchers anecdotally report better hair health and faster healing. Anti-aging is an exciting, but still understudied, potential effect of Ipamorelin. Keep an eye on future studies.
Bone density is another common victim of aging. As it goes down, the risk of fractures goes up. Postmenopausal women have a particularly high risk of brittle bones or osteoporosis, but taking care of bone health shouldn’t start when the realities of aging knock on the door. Ipamorelin has been promising in this area. Preliminary results show that the peptide regenerates bone density and stimulates new bone growth. [6]
Ipamorelin was the first selective growth hormone secretagogue (hormone that triggers the release of another hormone) to be synthesized. [7] Since then, it’s drawn interest because growth hormone, and the Growth Factor 1 that it triggers, have neuroprotective and neuro-regenerative effects — important for focus and memory. Human trials haven’t started yet, but some report improved mental clarity and reduced “brain fog.” Interesting for anyone who believes performance begins in the brain.
It’s already well-documented that growth hormone can “mobilize stored fat” — AKA, shred it. It’s no surprise that Ipamorelin has been of interest to researchers studying obesity [8], both for its potential to break fat down for energy and to improve insulin sensitivity. Stimulants like caffeine disrupt the body’s natural rhythms during this same process, but Ipamorelin (derived from ghrelin) relies on them. Scientists have called for further research into the potential fat loss benefits of Ipamorelin, so watch out for new studies!
The release of growth hormone is tied to sleep cycles. It peaks during slow-wave sleep. Studies have shown that four months of growth hormone therapy reverses sleep disturbances in deficient adults. [9] Ipamorelin is fascinating in this context, because it may put more restorative sleep within reach — as well as simply more hours of shut-eye.
This page has to end somewhere — but the potential applications of Ipamorelin don’t stop here. Early research has hinted at improved joint health (because of the collagen stimulation) and faster sprain recovery, and better digestive system functioning (what Ipamorelin was originally studied for), and at protecting the liver under stress. Read through the studies yourself. They’re worth your time.
The increase in growth hormone levels that Ipamorelin causes is of obvious interest to anyone studying muscle gains, fat loss, and recovery protocols — athletes and bodybuilders. Improved GH levels also, on the other hand, benefit people with sleep disorders, low bone density, and anyone who hopes to slow down (and potentially reverse) some of the most common signs of aging.
Ipamorelin might just have one job — triggering the release of more growth hormone — but the effects are surprisingly wide-ranging.
People investigating Ipamorelin often start with a 100 mcg dose once a day, just before bed. This dose establishes tolerance.
Adding zinc or magnesium to a protocol can strengthen the GH response — but steer clear of carbs in the hour before and after a dose. The most common side effects are redness around the site of administration, headaches, and slight nausea (although some studies have also found Ipamorelin to have an anti-nauea effect).
Reconstitute each 5 mg vial of Ipamorelin with 2 mL of bacteriostatic water. Swirl, gently, until it’s fully dissolved. Keep refrigerated. Ipamorelin should be used within 30 days for the best results; potency reduces over time.
Feel free to use our peptide calculator to see how much peptide to draw based on added BAC quantity.
How long should I wait to eat after Ipamorelin?
Eating makes your insulin spike, especially if you eat carbs. That can dull the mechanism of action Ipamorelin has. Most researchers fast for an hour before and after Ipamorelin.
Does Ipamorelin raise insulin?
It doesn’t, in contrast to GHRP-6 and MK-677. Ipamorelin is a selective peptide. It doesn’t raise insulin or cortisol levels.
Why take Ipamorelin at night?
Because your GH levels peak while you’re sleeping. You line your schedule up with your body’s when you plan your dose before you go to bed.
What does Ipamorelin do to the body?
Ipamorelin stimulates GH. That, in turn, might help with muscle growth, recovery, sleep, skin health, joint health, and fat burning. Some research hints that Ipamorelin also leads to better focus.
DISCLAIMER:
Our peptides can be used solely for in vitro experiments and cannot be:
Amino Acid Sequence: | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
---|---|
Molecular Weight: | 1419.556 g/mol |
CAS Number: | Not explicitly listed, but BPC-157 is often referred to by its synonyms like PL 14736 |
Molecular Formula: | C62H98N16O22 |
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