Hexarelin 5mg

Why Choose CellPeptides’ Hexarelin?

The quality of your peptide research depends on the quality of your peptides — and CellPeptides provides pharmaceutical-grade Hexarelin to start your studies off on the right foot. We’re a scientific and research company based in EU, which means you get EU-made, WHO/GMP and ISO 9001:2015 certified, Hexarelin you can count on to preserve the integrity of your studies.

With CellPeptides, you get:

• Hexarelin made to ≥99% purity, the highest standard for your peptide research.
• Third-party testing that allows you to independently verify the composition and purity.
• Fast global shipping in temperature-controlled packaging — and yes, insured and fully trackable, too.
• Flexible payment methods — not just credit cards and bank transfers, but also crypto.

We also, by the way, bring top-notch efficiency to our customer service. If you have any questions about Hexarelin, how to order, or shipping, we’ll get them answered right away.

How Does Hexarelin Work?

This is where Hexarelin gets really interesting, because it doesn’t work like other GH secretagogue peptides.

First, it binds to the GHSR-1a receptor in the brain, where it does pretty much what the natural hunger hormone ghrelin does — order a strong, pulsatile release on command (except without the hunger spike that ghrelin causes). It’s not growth hormone, but it does boost GH. That makes it possible to access the benefits, without the side effects.

Hexarelin also, on the other hand, binds to CD36 — a damage control protein that protects heart tissue, blood vessels, and immune cells. Other GHS peptides don’t do this, so it’s no surprise that much of the research done more recently has zoomed in on this part of its dual action. Hexarelin protects the heart from stress. It slashes inflammation, slows cell death down, and helps heart tissue heal and repair.

While Hexarelin does all that, it also works to improve lipid metabolism and vascular elasticity, somewhere in the background. Better blood flow and healthier cholesterol levels are a bonus.

Hexarelin in Research: Documented Effects on Heart Health, Muscle Growth, and Metabolism

Hexarelin is a peptide that goes deep rather than wide. Although it was initially studied as a potential treatment for growth hormone deficiency in children and adults, its cardioprotective effects have long since taken center stage. Curious about the most exciting findings so far? Perhaps these researched applications will inspire the direction of your own studies.

The Potential of Hexarelin as a Cardiovascular Shield

This is by far the most exciting area of research, because it’s where Hexarelin is unique. Ghrelin, the hunger hormone that Hexarelin mimics, does have some cardioprotective benefits — but those seen with Hexarelin are far stronger. Hexarelin improves heart function. It protects heart tissues against oxidative stress and reduces arterial plaque formation.

That makes it promising for a whole host of applications. Heart failure, cardiac fibrosis, atherosclerosis, and high cholesterol are just the beginning. Rebuilding heart health after a heart attack is another interesting use case. [1] The science is still in its early stages, but piling up quickly. Even more interestingly, research has demonstrated that the cardioprotective effects of Hexarelin are completely independent of its role as a GH booster. [2]

Muscle Preservation and Anti-Wasting Effects

Growth hormone — which Hexarelin nudges the body to release more of — has a strong anabolic effect. It helps people build more muscle, faster, and it does that by boosting IGF-1 levels. That makes Hexarelin an obvious candidate for anyone interested in building muscle, retaining muscle, and preventing wasting.

Studies have looked at its effect on patients with cancer, AIDS, and other muscle-wasting conditions. Human trials have concluded that Hexarelin makes it easier to hold onto lean mass, even during periods of severe caloric deficiency. What’s more, Hexarelin has this muscle-preserving benefit despite the fact that it doesn’t induce hunger and cravings. [3, 4]

Metabolic Regulation, Cholesterol, and Triglycerides

We’ve looked at the protective benefits Hexarelin has when it comes to the heart. Still in its early stages but no less fascinating is research into its potential to lower cholesterol and triglyceride levels. Animal models show positive results — and Hexarelin doesn’t only help with metabolic regulation in obese lab rats, but also in leaner specimens. [5, 6] That’s exciting, because it shows Hexarelin has metabolic effects that go far beyond the GH release that’s already been established.

(What about obesity studies? Curious minds want answers. It’s still early days, but studies in animal models have indeed been conducted, because of how Hexarelin impacts mitochondrial functioning. Watch that space closely.)

Hexarelin and the Potential for Longevity Studies

Researchers studying longevity — with a focus on quality of life and on health — should primarily look at the combined effects of Hexarelin in the areas we’ve already looked at. Its cardioprotective benefits touch every aspect of aging. Hexarelin activates autophagy in heart cells, a cleanup process that becomes less effective with age. [7] Animal models show it to reverse arterial stiffness.

Hexarelin has been very effective in reducing muscle loss in aging subjects, a process just as interesting for future human trials. Finally, because Hexarelin rescues mitochondria in heart and muscle tissues from oxidative damage [8], there’s a general energy and resilience angle wide open for exploration. Human data is limited. So far, however, it appears that Hexarelin isn’t a fountain of youth. It might, however, be of interest to researchers zooming in on “healthspan” as opposed to lifespan.

Who Might Consider Hexarelin?

Hexarelin research has come a long way — and although it’s a growth hormone booster, most research focuses on its cardioprotective effects. This targeted peptide is most interesting to people studying:

• Muscle mass development and preservation — athletes who are getting older, bodybuilders during cutting, or patients with cachexia due to cancer or chronic illness.
• Cardioprotective effects — after a heart attack and for general heart protection, including the potential to slash cholesterol levels.
• Looking at potential ways to counter mitochondrial and vascular degradation with age.

Hexarelin simulates the effects of ghrelin without its side effects (hunger!), but beyond that, this peptide’s ability to bind to the CD36 receptor has left the door wide open for future cardioprotective research.

Common Dosing Protocols for Hexarelin In-vitro Research Setting

CellPeptides provides research-grade Hexarelin to facilitate peptide research — but your study design is equally important. Established protocols typically begin with doses between 0.5 and 1 mg. These initial doses establish how the model responds. Researchers then slowly build up to standard dosing, which is between 1 and 2 mg.

Frequency depends on the research goal. However, daily doses or dosing on alternate days is typically used for research that looks at acute and short-term effects. Dosing Hexarelin weekly is uncommon, but some research designs do use it.

Store Hexarelin for no longer than ~60 days in its unopened state, at temperatures between 2 and 8 °C and in the fridge. Reconstitution is standard. Dilute a 5 mg vial with 2 mL of BAC water.

You can use our comprehensive peptide dosage calculator here to find out the doses you need to draw depending on how much BAC water you mix with the peptide.

FAQ

Is Hexarelin better than Ipamorelin?

That entirely depends on the research goal. Hexarelin gives a stronger GH pulse and has cardioprotective effects, but it might cause a slight cortisol spike. Ipamorelin is more often studied for long-term effects, and is less potent.

How quickly does Hexarelin work?

Hexarelin causes a GH spike very quickly — 15 to 30 minutes after a dose. The cardio benefits take longer to emerge, after two to four weeks of consistent dosing. Studies show peak effects at four to six weeks.

Does Hexarelin increase cortisol?

Slightly and temporarily. That bump increases energy mobilization. Hexarelin doesn’t cause chronically high cortisol for the duration of the research.

What is the difference between CJC-1295 and Hexarelin?

Good question, because these two do pop up in many of the same studies. CJC-1295 is a slow-release GH booster with effects that last for days. Hexarelin works more like natural spikes, and it has cardio effects that CJC-1295 doesn’t.

Does Hexarelin burn fat?

Indirectly, via fat oxidation. It does not have the cutting effects of AOD-9604, however.

DISCLAIMER:

Our peptides can be used solely for in vitro experiments and cannot be:

• Used in clinical trials involving humans
• Administered to humans as part of an experiment or investigation
• Supplied to another party for human investigational use

Scientific References

1. https://pmc.ncbi.nlm.nih.gov/articles/PMC4178518/
2. https://academic.oup.com/endo/article-abstract/140/9/4024/2990623
3. https://www.mdpi.com/1422-0067/20/18/4361
4. https://www.benthamdirect.com/content/journals/cn/10.2174/1570159X20666220915103613
5. https://academic.oup.com/endo/article/158/10/3174/3964576
6. https://www.researchgate.net/profile/Giuseppe-Rossoni-2/publication/12346860_Endocrine_metabolic_and_cardioprotective_effects_of_hexarelin_in_obese_Zucker_rats/links/0deec516cf0a28757d000000/Endocrine-metabolic-and-cardioprotective-effects-of-hexarelin-in-obese-Zucker-rats.pdf
7. https://www.ingentaconnect.com/content/govi/pharmaz/2019/00000074/00000008/art00007
8. https://academic.oup.com/endo/article-abstract/148/3/1009/2501576