GHK-Cu 50mg

50.49

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This copper-bound tripeptide (glycine, histidine, and lysine) is a master regulator of cellular repair. GHK-Cu dials down oxidative stress, rebuilds skin and blood vessels, and lowers inflammation by modulating thousands of genes — all with the same command: “Heal this.”

The kicker? Natural GHK levels drop dramatically with age. By age 60, people are left with less than half the GHK in their bloodstream than they had at 20. As GHK levels go down, so does the body’s ability to repair itself.

The synthetic version, GHK-Cu, delivers a copper-boosted repair kit. GHK-Cu stimulates collagen and elastin (3x production in fibroblasts) for more youthful skin, speeds up wound healing, protects against oxidative stress, and increases stem cell production. No wonder GHK-CU has been so popular among anti-aging researchers. The research applications are broad and exciting. They range from topical skincare to systemic recovery.

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      Why Choose CellPeptides’ GHK-Cu?

      Peptide research demands precision and careful planning. That starts with choosing a provider you can trust. CellPeptides is a EU-based (we also ship to USA with no issues whatsoever) research company that manufactures pharmaceutical-grade peptides — in a WHO/GMP and ISO 9001:2015 certified laboratory.

      Researchers choose CellPeptides as a reliable source of GHK-Cu because:

      • We offer 99% pure GHK-Cu — made with serious study in mind.
      • Use precision copper ratios (1:1 complex) for optimal bioavailability.
      • Are backed by independent lab tests. Read the latest report for yourself to check composition and purity.

      Our service? Just as precise. CellPeptides ships worldwide — fast, insured, and with a tracking code. Payment options include cryptocurrency as well as credit card and bank transfer. Our customer support is always available to answer your questions about peptides or ordering.

      How Does GHK-Cu Work?

      As GHK-Cu modules thousands of genes, it triggers a series of effects that all contribute to healing and regeneration — not skin deep, but at the genetic level. GHK-Cu strengthens the body’s defenses against DNA damage, rebuilds connective tissue, blood vessels, and skin, and fights inflammation. [1]

      GHK-Cu increases collagen and elastin production while breaking down damaged cells, gives fibroblasts a boost, and, research suggests, paves the way for new stem cell growth by “recruiting” repair cells to injured sites.

      The copper in GHK-Cu stabilizes the peptide, but it also works as a delivery system to make sure healing takes place where it’s needed. On top of that, GHK.

      GHK-Cu tells the body to make new collagen and elastin — two of the things that keep it young — while trashing damaged cells. That gives it immense research potential, and the studies that have emerged so far already show a lot of promise.

      GHK-Cu Potential Uses: Applications in Research

      Given its reputation as a “master switch” for youth and cell regeneration among biohackers, it is hardly surprising that much of the research into GHK-Cu so far has focused on its potential in restoring tissue health. That application is promising and already backed by a growing body of studies. It is not the only direction GHK-Cu research is taking, though.

      Curious what has already been studied? Peptide research has come a long way, and these are some of the most interesting results to date.

      GHK-Cu in Skin Regeneration and Anti-Aging Research

      Anti-aging research has advanced significantly in recent years, and a number of effective wrinkle-fighting compounds have been uncovered. A human trial conducted in 2024 showed, however, that GHK-Cu is the most potent of all of them. Even vitamin C and retinoic acid couldn’t compare. Seventy percent of participants treated with GHK-Cu saw a dramatic collagen boost that visibly decreased thinning and wrinkling, and tightened the skin around the eyes. [2]

      That same mechanism is equally interesting to people researching the scar-reduction potential of GHK-Cu. More than one study has found the healing and anti-inflammatory powers of GHK-Cu to be effective in treating scarring and burns. [3]

      Chronic and Acute Wound Repair Applications

      Diabetic ulcers have long been one of the most serious health threats to people with diabetes who, if these ulcers are left untreated, risk serious infections and even amputation. Can GHK-Cu help there, too? That is what researchers tried to find out in a study into diabetic wound care. The results were fascinating. People treated with GHK-Cu healed at twice the normal speed. The peptide GHK is not the only factor there. Copper is an antibacterial agent in its own right, with the potential to slash infection rates during this high-risk healing process. [4]

      Post-surgical wounds are another interesting candidate. Studies in animal models have shown that GHK-Cu has potential in this area, but further research still needs to be done.

      Follicle Revival and Hair Health

      GHK-Cu is also among the peptides that have been studied in the context of hair health. Two areas of interest have arisen — melanocyte reactivation (yes, gray hair reversal) and follicular revival. In people with various kinds of hair loss, including male pattern baldness, GHK-Cu was demonstrated to have the ability to increase follicle size and proliferation. That action is likely related to the fact that GHK-Cu stimulates the production of new stem cells.

      Hair health is less urgent than some of the other use cases for GHK-Cu, which explains why it is still understudied. New studies are still coming out, though, so take a look at new findings as they appear.

      GHK-Cu in the Treatment of Systemic Inflammation

      GHK-Cu has consistently demonstrated strong anti-inflammatory effects. These have, of course, made the peptide interesting to rheumatoid and osteoarthritis researchers. Both oral and systemic administration have been studied, with the finding that GHK-Cu has a positive impact on tissues far away from the site of administration. [5]

      Reduced cartilage degradation is one area where GHK-Cu has  potential, but its anti-inflammatory benefits are not limited to that. GHK-Cu also reduced collagen buildup in pulmonary fibrosis [8], so far seen in animal models.

      The Potential Brain Health Benefits of GHK-Cu

      Anyone familiar with neurodegenerative disorders like Alzheimer’s and Parkinson’s is likely to immediately understand why the anti-inflammatory and oxidative-stress-fighting effects of GHK-Cu have interesting implications for their management. Studies have already looked at GHK as a treatment option for cognitive decline, because of its ability to restore cells to a more youthful state. [7]

      Investigations are still underway. In the meantime, GHK-Cu is beginning to attract attention for its potential to positively impact cognitive health — in people at risk of neurodegenerative disorders and beyond [9].

      Who Might Consider GHK-Cu?

      GHK-Cu research has already looked at many different potential practical applications. It’s a restorative peptide. GHK-Cu tells the body to make new, more youthful elastin and collagen while cleaning up damaged cells. That mechanism makes GHK-Cu most interesting to people who want to investigate:

      • Skin health — wrinkle treatment, skin tightening, scar removal, and chronic wound healing are among the most-studied effects of GHK-Cu.
      • Hair restoration, whether in the context of male pattern baldness or other forms of alopecia [6]. Gray hair reversal research has lagged behind, but pigment revival is a fascinating area of study.
      • Chronic wounds, specifically those related to diabetes.

      GHK-Cu has, meanwhile, caught the attention of biohackers optimizing health for its potential to slow aging systemically. In the lungs, joints, and in the brain.

      Common Dosing Protocols for GHK-Cu In-vitro Research Setting

      Researchers investigating GHK-Cu have two administration options (topical (less potent) and subQ or IM injections (very potent))— both applications have shown results, depending on the area of study but overall injections are superior in many ways according to studies.

      • Skin health researchers generally use either 1 to 2 mg a day, or weekly 5 mg.
      • Hair rejuvenation research relies on systemic doses of 2 mg per week.
      • Chronic wound healing requires more potency, and a common protocol is to opt for 3-10 mg doses, once a week, until healing has been achieved.
      • For biohackers researching longevity, two weekly doses of 2-5 mg/week are a common choice — with cycles of eight weeks of GHK-Cu followed by a four week break.

      Researchers start with small doses of 0.1 mg to 0.5 mg sub-Q or IM, and gradually increase dosing from there. This helps with acclimatization and establishes tolerance.

      To reconstitute GHK-Cu, add 2 mL of BAC water to a 50 mg vial. Keep GHK-Cu cool and dark (in the fridge!) for no more than 30-60 days.
      You can use our comprehensive peptide dosage calculator here to visually see how much to peptide to draw depending on how much BAC water you add.

      FAQs

      Does GHK-Cu activate stem cells?

      It does. That’s one of its most interesting effects. GHK-Cu sends stem cells to damaged tissues as it releases SDF-1.

      Is GHK-Cu the same as copper peptides?

      Not quite. GHK-Cu is one kind of copper peptide. There are others, including Cu-GHK (which uses a different copper bond) and Copper Tripeptide-1.

      What are the potential side effects of GHK-Cu?

      Because of the copper content, blue or green urine is one of the more common side effects of GHK-Cu. This isn’t dangerous. Redness or itching at the site are also possible.

      What is the difference between GHK and GHK-Cu?

      GHK (the naturally-occuring version) doesn’t have copper. Copper increase biovailability, so GHK-Cu is more potent. (Plus, the body’s natural GHK declines with age.)

      DISCLAIMER:

      Our peptides can be used solely for in vitro experiments and cannot be:

      • Used in clinical trials involving humans
      • Administered to humans as part of an experiment or investigation
      • Supplied to another party for human investigational use

      Scientific References

      1. https://www.mdpi.com/1422-0067/19/7/1987
      2. https://pmc.ncbi.nlm.nih.gov/articles/PMC11830136/
      3. https://www.tandfonline.com/doi/abs/10.1163/156856208784909435
      4. https://www.cell.com/heliyon/fulltext/S2405-8440(24)14512-4
      5. https://onlinelibrary.wiley.com/doi/full/10.1002/jor.22831
      6. https://www.tandfonline.com/doi/10.1080/09546634.2018.1544405#abstract
      7. https://pmc.ncbi.nlm.nih.gov/articles/PMC11426299/
      8. https://www.sciencedirect.com/science/article/abs/pii/S0024320519310677
      9. https://onlinelibrary.wiley.com/doi/full/10.1155/2012/324832

       

      Amino Acid Sequence:

      Gly-His-Lys

      Molecular Weight:

      403.9 g/mol​

      Molecular Formula:

      C₁₄H₂₄CuN₆O₄

      CAS Number:

      49557-75-7

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