*while CellPeptides provides pure and pharma-grade peptides – they are only approved for non-human research use only. The below effects and info are research-based information.

Main Purposes of Selank Peptide

Anxiety reduction

Studies show that Selank has anxiolytic effects which helps calm its users without the use of sedatives. The anti-anxiety properties are as a result of the peptide’s ability to inhibit the breakdown of enkephalins.

Low levels of this pentapeptide have been known to trigger anxiety. Selank ensures their presence while keeping off the effects of other substances like benzodiazepine that may offer a calming effect but cause sedation or addiction.

Provide stress relief

Selank helps alleviate stress as it affects the release of stress related hormones like cortisol. This helps regulate the body’s response to stressors. It promotes quick adaptation to stressors and keeps at bay their biological impacts. As a result, you get to enjoy a less-stressful environment which helps to boost mental performance.

Enhance cognitive function

Studies have shown that Selank can help to improve memory, sharpen problem-solving skills, and enhance learning. This is because of its influence on the brain’s neurotransmitters which can impact intraneuronal communication and enhance cognitive processes.

Increase BDNF production

Selank usage helps to improve long-term and short-term memory. The peptide works on the neurotransmitter system, enhancing neurotrophic factors like Brain –derived neurotrophic factor (BDNF). BDNF plays a crucial role in the regulation of synaptic functions which is essential for learning and memory. Be aware that low levels of the compound have also been shown to heighten anxiety.

Selank Quantity and Forms

Quantity

Selank is yet to be officially approved for human use. As a result, there’s limited research on dosage quantities. However, available clinical research has provided some quantities depending on the form of medication you take.

Forms

Selank can be administered as subcutaneous or IM injections.

The effects are more long lasting as compared to nasal spray and the dosage can fall anywhere between 100 to 300 mcg. This is administered once daily.

Instructions

• Subcutaneous or IM injections should be administered once a day depending on the patient’s response starting from 100mcg up to 300mcg or more depending on effects.
• When using injection, it is important to have it done by a healthcare professional as precise dosing is very important.

While results can vary depending on individual response and tolerance, it’s best not to go beyond the recommended dosage amounts. The prescription should also not be longer than one to two weeks before an observation period of a full week thereafter.

Reconstituting Selank

If you choose the subcutaneous injection, you’ll need to reconstitute the powder. This involves mixing the lyophilized powder with a suitable solvent before administration.

The best solution for this is bacteriostatic water. Not only does this help to maintain quality and safety standards but it also helps improve the shelf life is the peptide is stored properly.

Here are the guidelines for proper reconstitution:

• Gather the necessary supplies for reconstitution i.e. the solvent and powder
• Determine the correct volume required for dosing. A calculator will come in clutch at this stage.
• Prepare the solvent by drawing required amount of bacteriostatic water from the vial.
• Steadily inject the solvent into the vial containing selank ensuring to spray the vial walls allowing it to flow down dissolving the powder
• Avoid shaking the vial but instead swirl until all Selank is dissolved.
• Store appropriately at refrigerated temperature of 2-8 degrees Celsius
• Remember to use disinfectant on the vials to avoid contamination.

How Does Selank Work?

Selank works by binding to GABA receptors thereby increasing the production of serotonin in the brain. Serotonin levels in the brain determine the mood, anxiety and happiness of an individual. Selank also influences the production of BNDF which is a protein that promotes the formation of new brain cells promoting brain health and neuroprotection.

Benefits of Selank

Reducing pain and Inflammation

Selank is particularly useful where chronic inflammations are a factor as it exhibits anti-inflammatory properties which can be beneficial to users with such conditions. It’s ability to disrupt the breakdown of enkephalins also helps to alleviate pain which is essential for people suffering from conditions like Fibromyalgia.

Features anti-viral properties

By influencing the immune system response, selank can restrict the reproduction of influenza (Flu) strain. This is particularly through the cytokine gene expression which improves the body’s ability to fight viral infections.

Anti-depressant

Selank works to regulate the production of neurotransmitters like dopamine and serotonin. This brings a calming effect on the body, improving mood and reduces the symptoms of depression.

Improving attention span and reduced mental fatigue

This peptide’s therapy influence on neurotransmitter systems plays a crucial role in improving focus and overall attention span. As a result, you get to enjoy extended brain functioning without brain fatigue which would be present without selank’s modulation and intervention.

Helps to manage cognitive disorders

With its influence on neurotransmitter systems, Selank allows for better brain functioning and neuroprotection. This promotes overall brain health by preventing cognitive decline while enhancing better cognitive abilities including focus, good memory and attention.

Mood enhancer

Selank helps in stabilizing mood swings and promotes consistent emotional state. This improves the mental wellbeing and overall health.

Improves sleep quality

While not one of the major uses of Selank, lower levels of anxiety and stress are more likely to promote improved sleep quality for its users.

Who Should Use Selank?

People with anxiety disorder

Selank has shown promise in the treatment of patients suffering from Generalize Anxiety Disorder (GAD). Selank has helped alleviate anxiety levels promoting a sense of calm without the dependency that is created by similar.

People suffering from stress and depression

Selank helps patients living under high stress conditions by lowering stress levels helping them cope. It helps to promote quick adaptation to stressors influencing their biological impacts. Selank influences the production of the neurotransmitter’s dopamine and serotonin. This helps in controlling mood of its users bringing a calming effect and improving overall mood.

People with chronic inflammation

This peptide therapy displays anti-inflammatory properties which are life changing to patients with chronic inflammation. It also influences the breakdown of enkephalins which helps relieve pain.

Individuals with low concentration

By lowering stress and anxiety, Selank’s helps the patient achieve higher concentration levels. This makes it easier for individuals to carry out activities that require high focus levels such as leaning.

Patients suffering from memory loss

Selank influences the production of BDNF which is responsible for neuron survival and growth, modulating neurotransmitters, involved in neuroplasticity and is essential for learning and memory. By increasing the production of BDNF, Selank helps bolster the memory of its users.

Potential Effects of Selank

When used with the guidance of a professional medical expert, Selank is generally safe to use if the right dosage and precautions are implemented. Regardless, as with most drugs, there are some side effects and safety considerations to make.

Common side effects include:

• Fatigue
• Headaches
• Nasal discomfort
• Redness at injection site
• Failure to experience any changes in anxiety or mood

Less common side effects include:

• Hair loss
• Dizziness
• Nausea
• Allergic reactions

You need to quickly consult a healthcare practitioner if any of these symptoms arise as they tend to be more severe ad can prove fatal.

When Will the Results of Selank Become Obvious?

The timeline for which you may observe changes varies depending on the form of peptide therapy you are under and the dosage quantity. Individual response can also influence the outcome.

However, if using the nasal spray, you can feel its effects within the first twenty minutes. The injection takes about an hour for the effects to be felt. And, it can last for up to 12 hours in both cases. The changes also become more pronounced with continuous use.

FAQs

Does Selank cause weight gain?

No. At the moment there is yet for a connection to be established between the two.

Can Selank be used in combination with other drugs?

There are potential drug interactions that can bring about severe side effects. This is why you should first consult a health specialist before you embark on the peptide therapy.

Is Selank cycling advisable?

Yes. It is known to help maintain drug efficacy and prevent tolerance.The breaks you take in between treatments help to ensure that your body doesn’t build resistant to the medication.

What is the half-life of Selank?

Selank is quickly metabolized within the body with a half-life ranging between minutes and at most an hour. This is why it’s effects don’t last long compared to other drugs.

Does Selank build muscle?

No. The peptide doesn’t react with any part of the body in a way that enables or supports muscle growth.

References

Filatova E, Malygina D, Poletaeva I, et al. GABA, Selank, and Olanzapine affect the expression of genes involved in GABAergic neurotransmission in IMR-32 cells. Front Pharmacol. 2017;8:89. doi: 10.3389/fphar.2017.00089

Volkova A, Malygina D, Ivanova N, et al. Selank administration affects the expression of some genes involved in GABAergic neurotransmission. Front Pharmacol. 2016;7:31. doi:10.3389/fphar.2016.00031

Kolik LG, Bashkatova VG, Vakhitova YV, et al. Selank, peptide analogue of tuftsin, protects against ethanol-induced memory impairment by regulating BDNF content in the hippocampus and prefrontal cortex in rats. Bull Exp Biol Med. 2019;167(5):641-644.  doi:10.1007/s10517-019-04550-z

Yasenyavskaya AL, Andreeva LA, Dolotov OV, et al. The influence of Selank on the level of cytokines under the conditions of “social” stress. Curr Rev Clin Exp Pharmacol. 2021;16(2):162-167. doi:10.2174/2772432816666210610120229