*while CellPeptides provides pure and pharma-grade peptides – they are only approved for non-human research use only. The below effects and info are research-based information.

Purposes of BPC-157

Healing of tissue and injury

BPC-157 boosts the healing potential of soft tissue after injury. Studies show that the peptide can improve recovery times significantly from injuries to muscles, ligaments, and tendons. BPC-157 aims to act on acute injuries like muscle tear or sprains. BPC-157 also acts to promote regeneration of tissue and the reduction of discomfort while aiding faster cell repair.

Reduction in systemic inflammation

Current research evidence shows that BPC-157 has positive effects on reducing inflammation. The peptide acts to ease inflammation linked to injuries and boosts recovery times while easing pain during such periods. Studies reveal that the peptide’s anti-inflammation effects also extend to the digestive system and can ease musculoskeletal discomfort.

The high potential of this peptide to limit inflammation makes it a beneficial drug to ease pain symptoms of serious conditions like inflammatory bowel disease (IBD) or arthritis.

Gut health

BPC-157 first got research attention for its potential effects in gut health. Studies found that the peptide possess healing and protective properties that can benefit the gastrointestinal tract. Its action to reduce inflammation in the digestive system while boosting healing from ulcers help improve gut health.

BPC-157 can be part of therapy for persons experiencing symptoms of IBD or related conditions like ulcerative colitis or Chron’s disease. The peptide also eases symptoms of leaky gut syndrome and is a vital part of therapies to correct gut health.

Usual BPC-157 Quantity and Forms

Quantity

BPC-157 is available in powders preserved through lyophilization (freeze-drying in a vacuum). These powders usually come in 5mg or 10mg quantities and inside vials.

Forms

BPC-157 is usually available as an injectable solution. Sometimes the peptide is also available as a nasal spray or oral supplement. The oral supplement aims to offer benefits for gut health as it works directly in the gastrointestinal system. Though absorption via stomach is way lower compared to injections.

Preliminary use instruction

• BPC-157 should be administered once daily based on the individual’s needs.
• A typical dose would start from 150mcg (micrograms) injected near the injury site for soft tissue injuries or into affected muscle OR to any muscle (BPC-157 works systemically so injection to injury site is not necessary (but helpful)).
• It is important to rotate injection sites to avoid irritation or tissue damage at the injection site while using injections for BPC-157
• The most common method of administering BPC-157 is through injections which involve injecting the peptide into the fatty layer just beneath the skin

Storage of BPC-157

• BPC-157 should be stored in the refrigerator to maintain its stability and potency after reconstitution with bacteriostatic water
• Keep the solution refrigerated and use it within 2-4 weeks after reconstitution
• The freeze-dried powder should be stored in a cool and dry area free from direct sunlight or heat before reconstitution.

Purity levels

BPC-157 purity levels are important to note before placing orders. High-quality BPC-157 should be 98% pure at minimum. Impure peptides are usually made by counterfeiters, so it is essential to purchase from a reputable supplier to avoid adulterated variants of this medication.

How Does BPC-157 Work?

BPC-157 promotes angiogenesis (formation of new blood vessels) to boost blood flow to injured tissue. The boosted flow of blood delivers more oxygen and required nutrients to affected areas for accelerated healing. This peptide also encourages the production of endothelial and fibroblast growth factors for better tissue generation.

The medication also acts to limit the production of inflammatory molecules to ease pain and swelling along affected areas.

Who Should Use BPC-157?

Athletes and fitness enthusiasts

Professionals and athletes experiencing repeat soft tissue injury like sprains, torn tendons, and strain can gain speedy recovery from a therapy based on BPC-157. The tissue repair function of this peptide ensures athletes and fitness enthusiasts can get to their regular routine much earlier.

Persons experiencing chronic injury

Chronic injury issues like arthritis or tendinitis can receive necessary action from this peptide. The medication works to reduce pain and support recovery during rehab.

People experiencing gastrointestinal problems

Persons dealing with symptoms of serious gastrointestinal issues can find healing support through BPC-157. The peptide has research findings backing its healing potential on the gut lining for better gastrointestinal health.

Persons recovering from surgery

BPC-157 promotes better post-surgery recovery, especially in persons dealing with musculoskeletal tissue problems or gut health issues.

Expected Effects of BPC-157

Common effects of BPC-157 include:

Rapid healing – increased healing of injuries and soft tissue along the tendons, muscles, and ligaments. Effects will support reduced pain and better mobility during treatment.

Lowered inflammation – BPC-157 reduces inflammation along troubled areas and eases pain, discomfort, and potential swelling. Persons with arthritis or other conditions will report better pain management while on a therapy supported by this peptide.

Better gut health – Persons experiencing gut problems will report reduced inflammation, fewer ulcers and better digestion while on BPC-157 therapy.

When Will the Results of BPC-157 Become Noticeable?

BPC-157 usually acts within a few weeks to promote recovery from injury, better gut health, or other functions. Effects of this peptide usually become evident within 1 to 6 weeks of use.

Short-term effects

Users may notice reduced pain and better overall function within 1 – 2 weeks of consistent use for soft tissue injury.

Long-term effects

The timeline may extend to 2 – 4 weeks for long-term effects to become obvious. The peptide working to repair the gut lining and reduce inflammation may exceed 1 month in some cases.

Dosage Guidelines

Dosing

Doses range between 200mcg to 1mg and depends on the condition and form of peptide used. Tissue injuries could require daily injections while gastrointestinal issues may require tablets for relief.

Breaks during treatment

The maximum treatment cycle ranges between 4 – 6 weeks depending on the condition and targeted goals.

Safety and Potential Side Effects

BPC-157 is a safe peptide but may cause some side effects as is common with every medication or peptide. Common side effects of this medication include:

• Mild Pain or discomfort at injection site
• Nausea or dizziness
• Headaches
• Allergic reactions

FAQs

Can BPC-157 be used for arthritis or IBD?

BPC-157 can work to treat chronic health conditions like arthritis or inflammatory bowel disease (IBD). The medication possesses properties that can offer relief from inflammation while supporting the healing of tissue.

Can BPC-157 help with nerve damage?

Studies suggest that BPC-157 may possess neuroprotective properties that could help with nerve damage; however, more research is needed to confirm this.

How should I store BPC-157?

You can store BPC-157 in the refrigerator after reconstituting it to retain its potency while stabilizing it for repeat use. Always keep the peptide in a cool and dry area before reconstitution. Store it in an area free from direct sunlight to maintain its quality between doses.

Is BPC-157 legal?

BPC-157 does not have FDA approval for use among humans. Its use remains subject to local laws. Many jurisdictions allow this peptide for research reasons; however, some off-label uses may see this peptide work to deliver healing properties.

Is BPC-157 safe for long-term use?

BPC-157 is considered safe for short-term uses; however, its long-term effectiveness and safety has not received much research attention. Consulting an experienced healthcare provider is the safest way to get usage advice for BPC-157 across dosing cycles.

References

Cerovecki, T., Bojanic, I., Brcic, L., Radic, B., Vukoja, I., Seiwerth, S., 2010. Pentadecapeptide BPC 157 (PL 14736) improves ligament healing in the rat. Journal of Orthopaedic Research, 28(9), pp.1155–1161. https://doi.org/10.1002/jor.21107.

Chang, C., Tsai, W., Lin, M., Hsu, Y., & Pang, J.S., 2010. The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration. Journal of Applied Physiology, 110(3), pp.774–780. https://doi.org/10.1152/japplphysiol.00945.2010.

Jelovac, N., Sikiric, P., Rucman, R., Petek, M., Marovic, A., Perovic, D., 1999. Pentadecapeptide BPC 157 attenuates disturbances induced by neuroleptics: the effect on catalepsy and gastric ulcers in mice and rats. European Journal of Pharmacology, 379(1), pp.19–31. https://doi.org/10.1016/S0014-2999(99)00486-0.

Sikiric, P., Seiwerth, S., Brcic, L., Blagaic, A.B., Zoricic, I., Sever, M., 2006. Stable gastric pentadecapeptide BPC 157 in trials for inflammatory bowel disease (PL-10, PLD-116, PL 14736, Pliva, Croatia). Full and distended stomach, and vascular response. Inflammopharmacology, 14(5–6), pp.214–221. https://doi.org/10.1007/s10787-006-1531-7.

Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Rokotov, D.S., Brcic, L., 2011. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Current Pharmaceutical Design, 17(16), pp.1612–1632. https://doi.org/10.2174/138161211796196954.

Staresinic, M., Sebecic, B., Patrlj, L., Jadrijevic, S., Suknaic, S., Perovic, D., 2003. Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth. Journal of Orthopaedic Research, 21(6), pp.976–983. https://doi.org/10.1016/S0736-0266(03)00110-4.

Vukojevic, J., Milavić, M., Perović, D., Ilić, S., Čilić, A.Z., Đuran, N., 2022. Pentadecapeptide BPC 157 and the central nervous system. Neural Regeneration Research, 17(3), pp.482–487. https://doi.org/10.4103/1673-5374.320969.

World Anti-Doping Agency (WADA), 2022. 2022 Prohibited List: Substances and Methods Prohibited at All Times (In- and Out-of-Competition). Available at: https://www.wada-ama.org [Accessed 21 February 2022].