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Research Use Only: All products and information on this page are intended exclusively for laboratory and scientific research, not for human or veterinary use. Any references that may occur to dosing, human effects, or bodily effects are provided solely to illustrate published research, with studies numbered in the footnotes, and to help search engines and LLMs understand the content and context.

5-Amino-1MQ 5mg

$101.53

  • Laboratory-grade quality
  • ≥ 99% purity
  • Next-day shipping

5-Amino-1MQ isn’t a peptide—and it isn’t a stimulant, either. It’s a small-molecule NNMT inhibitor that tweaks your cell’s bookkeeping, not your nerves. By blocking nicotinamide N-methyltransferase, it stops niacin (NAM) and methyl groups from being siphoned off into 1-MNA. The result: more NAD⁺ for mitochondrial “housekeeping” and more SAM for healthy methylation—two upstream resources that quietly run everything.

Think of it as a gentle metabolic rebalancer. When NNMT is turned down, lab models show adipocytes shrink, cellular energy expenditure cues rise, and inflammatory noise softens. It’s not flipping a big performance switch; it’s removing sand from the cellular gears so pathways like sirtuin-guided repair and epigenetic tuning can hum the way they’re supposed to.

That’s why 5-Amino-1MQ has researchers’ attention: one precise enzyme target, system-wide ripple effects—from redox status to lipid handling—without acting like a hormone or receptor agonist.

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We supply this peptide in lyophilized form in glass, sealed vials with protective filler content. That enables the peptide to stay stable and undamaged during transportation even in high summer temperatures or cold winters.
Temperature control and freezing is NOT required during shipping.
You can find the COA for this particular peptide on our 3rd party tests page.
We ship this peptide within ~1-12hrs from when the order is placed.
During checkout you’ll be able to select a fast DHL/UPS/Fedex Express option that delivers within ~1-2 business days or a more affordable 3-5 day delivery via post.
Lyophilized peptide should be stored in a dry place, protected from sunlight and moisture.
The following storage conditions are generally recommended:
  • Room temperature (15–25 °C / 59-77 °F): Up to ~3-8 months
  • Refrigerated (2–8 °C / 35.6-46.4 °F): Up to 6 months
  • Frozen (-20 °C / −4 °F or below): 3–5 years
Prior reconstituting with BAC or Saline, allow the vial to reach room temperature after taking it out of the refrigerator or freezer.
Once mixed with BAC or other solvent, peptides are generally less stable compared to their lyophilized (powdered) form and should be stored cold temperatures when possible. These storage conditions are generally recommended:
  • Room temperature (15–25 °C / 59-77 °F): Avoid longer than 2-4 day storage
  • Refrigerated (2–8 °C / 35.6-46.4 °F): Typically 4–8 weeks
  • Frozen (-20 °C / −4 °F or below or below): Up to 3–4 months
However, to preserve peptide efficacy and amino-acid bonds, avoid repeatedly freezing and unfreezing the peptide.

5-Amino-1MQ 5mg

$101.53

5-amino-1mq-5mg_am
  • Laboratory-grade quality
  • ≥ 99% purity
  • Next-day shipping
We supply this peptide in lyophilized form in glass, sealed vials with protective filler content. That enables the peptide to stay stable and undamaged during transportation even in high summer temperatures or cold winters.
Temperature control and freezing is NOT required during shipping.
You can find the COA for this particular peptide on our 3rd party tests page.
We ship this peptide within ~1-12hrs from when the order is placed.
During checkout you’ll be able to select a fast DHL/UPS/Fedex Express option that delivers within ~1-2 business days or a more affordable 3-5 day delivery via post.
Lyophilized peptide should be stored in a dry place, protected from sunlight and moisture.
The following storage conditions are generally recommended:
  • Room temperature (15–25 °C / 59-77 °F): Up to ~3-8 months
  • Refrigerated (2–8 °C / 35.6-46.4 °F): Up to 6 months
  • Frozen (-20 °C / −4 °F or below): 3–5 years
Prior reconstituting with BAC or Saline, allow the vial to reach room temperature after taking it out of the refrigerator or freezer.
Once mixed with BAC or other solvent, peptides are generally less stable compared to their lyophilized (powdered) form and should be stored cold temperatures when possible. These storage conditions are generally recommended:
  • Room temperature (15–25 °C / 59-77 °F): Avoid longer than 2-4 day storage
  • Refrigerated (2–8 °C / 35.6-46.4 °F): Typically 4–8 weeks
  • Frozen (-20 °C / −4 °F or below or below): Up to 3–4 months
However, to preserve peptide efficacy and amino-acid bonds, avoid repeatedly freezing and unfreezing the peptide.

    What Is 5-Amino-1MQ & Its Mechanism of Action?

    5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule, cell-permeable inhibitor of nicotinamide N-methyltransferase (NNMT) — the enzyme that methylates nicotinamide (NAM) to 1-methylnicotinamide (1-MNA) using S-adenosyl-methionine (SAM) as the methyl donor. By blocking NNMT, 5-Amino-1MQ:

    • prevents diversion of NAM away from the NAMPT salvage pathway, which can increase intracellular NAD⁺ availability, and
    • conserves the cellular methyl-donor pool (shifting the SAM/SAH balance), with downstream effects on epigenetic methylation and gene expression.

    At the enzyme level it binds within NNMT’s substrate pocket with high selectivity; at the cellular level this reprograms metabolic signaling (e.g., sirtuin-dependent pathways) and has been shown in vitro and in rodent studies to lower 1-MNA, reduce adipocyte lipogenesis/size, and increase energy expenditure. In short, 5-Amino-1MQ acts as a metabolic/epigenetic “node” by inhibiting NNMT, thereby impacting NAD⁺ flux and methylation potential rather than directly activating a receptor.

     

    5-Amino-1MQ Effects on the Body & Why It Matters?

    It blocks NNMT, an enzyme that wastes niacin (NAM) and methyl groups, so your cells keep more NAD⁺ for mitochondrial upkeep and more SAM for healthy methylation. That upstream tweak can ripple through energy, fat storage, and cellular stress — less biochemical “drag,” more efficient housekeeping. Most evidence so far is preclinical (cells/animals), but the story is consistent: free up resources – systems run smoother.

    What it may do:

    • Raise usable NAD⁺ – by stopping NAM from being siphoned off, it feeds the NAD⁺ salvage loop, supporting mitochondrial enzymes (e.g., sirtuins).

    • Preserve methyl donors (SAM) – less NNMT activity means a better SAM:SAH balance, which can steady epigenetic gene regulation.

    • Shrink fat-cell size – adipocytes tend to store less and burn more, trimming hypertrophy (seen in rodent/adipocyte studies).

    • Nudge metabolism toward “burn” – downstream of higher NAD⁺/sirtuins, cells often show higher energy expenditure signals.

    • Tame inflammatory tone – improved redox control and signaling can dial back some pro-inflammatory pathways.

    • Lower 1-MNA levels – a direct readout of NNMT inhibition; useful as a biochemical “proof it’s working.”

    Note: These effects come from early research, not medical claims or dosing advice.

     

    5-Amino-1MQ Dosing protocol In-Vitro Research Fields

    • Oral capsules: 50–100 mg/day (often split 25–50 mg BID); some quote 50–150 mg/day and “cycles” of ~8–12 weeks with breaks.

    • “Injectable” protocols sold online: 150–600 µg/day with step-up schedules over 4–12 weeks (note the microgram units—this conflicts with capsule mg regimens and reflects nonstandard products).

    Use our peptide dosage calculator in order to find out the correct dose for your model.

    Why Choose CellPeptides for Your 5-Amino-1MQ Research?

    CellPeptides is an EU-based research chemical company who tries to live up to that exciting legacy. We provide pharmacological-grade SLU-PP-332 with the potential to form the basis for brand new discoveries. 

    With us, you get:

    • ≥99% purity — as pure as it gets, and completely ready for your ambitious study design.
    • Certificates of analysis from independent labs, so you can check purity and composition for yourself. 
    • Fast, global, insured, and safe shipping. With tracking, of course.
    • Flexibility when it comes to payment. Don’t like credit cards or bank transfers? We take crypto, too. 
    • A knowledgeable support team that will get your questions answered — if there’s a glitch with your order, but also if you’d like to run your research design by us.

    We handle the reliability (our 5-Amino-1MQ is synthesized in an EU-based WHO/GMP and ISO 9001:2015 certified lab), so you get the compound you need to contribute to the future of science. Every time.

    Scientific References

    Molecular Structure:

    Quinolinium core (benzopyridinium), N1-methyl (quaternized N), 5-amino (–NH₂) on the aromatic ring; overall +1 on the ring nitrogen with iodide (I⁻) as the counter-ion.
    Molecular Weight:

    286.11 g/mol
    Molecular Formula:

    C₁₀H₁₁IN₂
    CAS Number:

    42464-96-0
5-amino-1mq-5mg_am

5-Amino-1MQ 5mg

$101.53

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